Researchers discovered the key cause of type 2 diabetes

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Researchers discovered the key cause of type 2 diabetes

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BY AYESHA GULZAR

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A team of researchers from the University of Oxford revealed that glucose metabolites, rather than glucose itself, play a key role in type 2 diabetes.

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High blood glucose damages the function of pancreatic beta-cells. Hence these cells cannot release enough Insulin hormone, leading to the progression of type 2 diabetes.

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Reducing the rate at which glucose is metabolized could offer a new way to treat the disease.

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WHO says, about 422 million people worldwide have diabetes. A vast majority of them suffer from type 2 diabetes.

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Blood glucose is the main source of energy and comes mainly from food intake. Insulin, a hormone made by pancreatic beta cells, helps glucose get into cells to be used for energy.

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In type 2 diabetes, the body doesn't make enough insulin or doesn't use insulin well. Too much glucose then stays in the blood, and not enough reaches the cells.

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While researchers have known that chronically elevated blood sugar leads to a progressive decline in beta-cell function.

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